Stochastic modeling of carcinogenesis: State space models and estimation of parameters
نویسندگان
چکیده
منابع مشابه
Stochastic Modeling of Carcinogenesis
Carcinogenesis is the transformation of normal cells into cancer cells. This process has been shown to be of a multistage nature, with stem cells that go through a series of genetic and epigenetic changes that eventually lead to a malignancy. Since the origins of the multistage theory in the 1950s, mathematical modeling has played a prominent role in the investigation of the mechanisms of carci...
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ژورنال
عنوان ژورنال: Discrete and Continuous Dynamical Systems - Series B
سال: 2003
ISSN: 1531-3492
DOI: 10.3934/dcdsb.2004.4.297